The Merian Gärten are named after the renowned Swiss botanist and naturalist, Maria Sibylla Merian (1647–1717). Maria Sibylla Merian was a pioneering figure in the field of entomology and an accomplished botanical artist. Her contributions to science and art made her a celebrated figure in her time.

The idea for the Merian Gärten was conceived in the late 19th century when the city of Basel decided to establish a botanical garden dedicated to Maria Sibylla Merian's work. The garden aimed to showcase the diverse plant species she had illustrated and studied.

In 1905, the Merian Gärten officially opened to the public. The original location of the gardens was at Schänzli, near the Rhine River. The gardens featured a variety of themed gardens, including a butterfly house, a medicinal plant garden, an orchid house, and a water lily pond.

In 2013, the Merian Gärten underwent a significant transformation and relocation. The gardens were moved to a new site near Brüglingen, a park area in Basel. The new location provided more space and opportunities for expansion.

The new Merian Gärten opened in 2016, offering visitors an enhanced experience with beautifully designed gardens, interactive exhibits, educational programs, and research facilities. The gardens continue to celebrate the life and work of Maria Sibylla Merian, showcasing her botanical illustrations, her passion for nature, and her scientific contributions.

Today, the Merian Gärten remain a popular attraction for both locals and tourists alike. Visitors can explore the various gardens, immerse themselves in the diverse plant collections, and learn about the rich botanical heritage of Basel.